Why the liver can’t always heal itself after quitting alcohol, scientists explain

New research reveals why alcohol-damaged livers cannot heal themselves. Liver cells get stuck in a repair limbo, unable to fully regenerate. RNA splicing problems and a missing protein, ESRP2, prevent tissue regrowth. Inflammation further suppresses ESRP2. These findings could lead to new treatments for alcohol-related liver disease, providing alternatives to transplants.

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